December 12, 2018
Use of bepridil against filovirus infections
Bedripil twice a day leads to 90% survival in a lethal Marburgvirus-infected mouse model
Journal Watch
December 12, 2018
Parallel study of HIV vaccine candidates in humans and rhesus monkeys
The mosaic Ad26/Ad26 plus gp140 HIV-1 vaccine induces comparable and robust immune responses in humans and rhesus monkeys and provides significant protection against repetitive heterologous SHIV challenges in rhesus monkeys
December 11, 2018
Effect of treatment with tenofovir on telomere length in HIV-infected patients
Antiretroviral-naive HIV-infected adults on ritonavir-boosted darunavir and tenofovir disoproxil fumarate/emtricitabine experience a significant higher increase in blood telomere length than those receiving ritonavir-boosted darunavir and raltegravir
December 11, 2018
Efficacy of favipiravir against Sudan Ebolavirus in guinea pigs
Favipiravir has significant antiviral activity against Sudan Ebolavirus, both in vitro and in a guinea pig animal model
December 10, 2018
Characterisation of cross-reactive broadly neutralising antibodies against HIV-1
New maps of HIV viral escape from a broadly neutralising antibody identify pathways of resistance and provide a strategy to improve the breadth or potency of future vaccine-induced antibodies against HIV Env’s fusion peptide
December 10, 2018
Relationship between RNA viral mutations and virulence
For many RNA viruses, within-host spread is associated with viral replicative speed rather than the standing genetic diversity as previously assumed
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