Guidelines

CMV monitoring in HSCT:

Management of Cytomegalovirus Infection in Haemopoietic Stem Cell Transplantation

Joint document on Management of Cytomegalovirus Infection in Haemopoietic Stem Cell Transplantation by working group from the CVN and BCSH: on behalf of the British Committee for Standards in Haematology, British Society of Blood and Marrow Transplantation and the UK Clinical Virology Network.

Virology related guidelines

Please contact Eleri Wilson-Davies (UK CVN Website & Communications secretary) via email ([email protected]) with the details of virology related guidelines to be added to this page. Please report any link which fails.

Blood-borne viruses

• BASHH: British Association for Sexual Health and HIV – Current Guidelines
• BHIVA: British HIV Association – Current guidelines
• CHIVA: Children’s HIV Association – Guidelines
• EASL: European Association for the Study of the Liver – Guidelines
• United Kingdom Advisory Panel for Healthcare Workers Infected with Bloodborne Viruses: Assessing the risk of iatrogenic transmissions to patients from healthcare workers diagnosed with bloodborne virus infection in the absence of an index case: advice for local incident management teams

• Hepatitis B virus
• EASL: European Association for the Study of the Liver: Management of Chronic Hepatitis B
• EASL: Management of chronic hepatitis B in childhood: ESPGHAN clinical practice guidelines
• Hepatitis B: the green book, chapter 18
• DoH: Hepatitis B Infected Health Care Workers: Guidance on Implementation of Health Service Circular 2000/020
• DoH: Hepatitis B infected healthcare workers and antiviral therapy
• PHE: Hepatitis B: guidance, data and analysis including:
  • Inoculation injuries and children in schools and similar settings
  • Infection prevention and control guidelines for blood glucose monitoring in care homes
  • Hepatitis B in residential and boarding schools
  • Immunoglobulin: when to use

• Hepatitis C virus
• EASL: European Association for the Study of the Liver: EASL Recommendations on Treatment of Hepatitis C 2015
• EASL Clinical Practice Guidelines: Management of hepatitis C virus infection

• HIV
• BHIVA: British HIV Association – Current Guidelines
• CHIVA: Children’s HIV Association – Guidelines
• UK Advisory Panel for Healthcare Workers Infected with Bloodborne Viruses (UKAP): HIV-infected healthcare workers and exposure prone procedures

Gastroenterology

• European evidence-based consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease

• Hepatitis A virus
• PHE: Hepatitis A: guidance, data and analysis including:
  • Guidance for the Prevention and Control of Hepatitis A Infection
  • Immunoglobulin: when to use
  • Infection control in schools
• Hepatitis A: the green book, chapter 17

• Hepatitis E virus
• PHE: Hepatitis E: guidance, data and analysis including:
  • Public health operational guidelines for hepatitis E

• Norovirus
• PHE: Norovirus: guidance, data and analysis including:
  • Guidelines for the management of norovirus outbreaks in acute and community health and social care settings

“The Green Book”: Immunisation against infectious disease

Immunoglobulin: when to use including:

• VZV
• HAV
• HBV
• Measles
• Mumps
• Polio
• Rabies

Analysis of the effectiveness of intra-muscular human normal immunoglobulin (HNIG) for measles prophylaxis

Infection control

• PHE: Infection control precautions to minimise transmission of acute respiratory tract infections in healthcare settings

Neurology

• Management of suspected viral encephalitis in adults – Association of British Neurologists and British Infection Association National Guidelines
• Management of suspected viral encephalitis in children – Association of British Neurologists and British Paediatric Allergy, Immunology and Infection Group National Guidelines
• National polio guidelines – Public Health England

Obstetrics and gynaecology

• RCOG: Chickenpox in Pregnancy (Green-top Guideline No. 13)
• PHE: Immunoglobulin: when to use
• HPA: Guidance on Viral Rash in Pregnancy

Paediatrics

• Evidence based management guidelines for the detection and treatment of congenital CMV

Rabies

• PHE: Rabies: risk assessment, post-exposure treatment, management including:
  
  • PHE guidelines on rabies post-exposure treatment (June 2015)
  • Rabies risk assessment: treatment after exposure to bats
  • Immunoglobulin: when to use
• Rabies: the green book, chapter 27
• Health Protection Scotland: Rabies: Guidance on Prophylaxis and Management in Humans in Scotland

Renal

• Department of Health: Good practice guidelines for renal dialysis/transplantation units: prevention and control of blood-borne virus infection
  including Addendum: Guidelines for dialysis away from base (DAFB)

Respiratory

• Avian influenza
• Public Health England: Avian influenza: guidance and algorithms for managing human cases

• Middle East respiratory syndrome coronavirus (MERS-CoV)
• Public Health England: Middle East respiratory syndrome coronavirus (MERS-CoV): clinical management and guidance
• Health Protection Scotland: MERS-CoV

• Seasonal influenza
• Public Health England:
  • Seasonal influenza: guidance, data and analysis
  • Influenza: treatment and prophylaxis using anti-viral agents including:
    • PHE guidance on use of antiviral agents for the treatment and prophylaxis of seasonal influenza (2015−16)
    • The use of antivirals for the treatment and prophylaxis of influenza – PHE summary of current guidance for healthcare professionals
    • Letter to clinicians regarding the use of antivirals in influenza
• Health Protection Scotland:
  • Guidance on use of antiviral agents for the treatment and prophylaxis of influenza, 2015-16
  • Seasonal influenza

Royal College of Pathologists

• National minimum retesting intervals in pathology A final report detailing consensus recommendations for minimum retesting intervals for use in pathology

SaBTO: Advisory Committee on the Safety of Blood Tissues and Organs

• Guidance on the microbiological safety of human organs, tissues and cells used in transplantation
• Advice Concerning Organ Donation and Seasonal Influenza
• West Nile virus and solid organ transplantation: SaBTO statement
• SaBTO report of the Cytomegalovirus Steering Group

SIMs: UK Standards for Microbiology Investigations

• Standards for Microbiology Investigations

Sexually Transmitted Infections

• BASHH: British Association for Sexual Health and HIV – Current Guidelines
• Sexually Transmitted Infections in Primary Care

Transplant

• Diagnosis of post-transplant lymphoproliferative disorder in solid organ transplant recipients – BCSH and BTS Guidelines
• British Transplantation Society Guidelines including:
  • British Transplantation Society Guidelines for the Prevention and Management of CMV Disease after Solid Organ Transplantation
  • Diagnosis of post-transplant lymphoproliferative disorder in solid organ transplant recipients (joint with BSCH)

Transport of Infectious Substances

• Department of Health: Changes to infectious substances transport procedures in 2005 – The regulations that apply to laboratory and health care premises
• World Health Organisation: Guidance on regulations for the Transport of Infectious Substances 2015–2016 – See page 26-27 for ‘Packing Instruction P620’

Viral haemorrhagic fever

• Advisory Committee on Dangerous Pathogens: Viral haemorrhagic fever: ACDP algorithm and guidance on management of patients
• Health Protection Scotland: Ebola and other Viral Haemorrhagic Fevers

Zika virus

• PHE: Zika virus
• CDC: Zika virus

Please contact Eleri Wilson-Davies (UK CVN Website & Communications secretary) via email ([email protected]) with the details of virology related guidelines to be added to this page. Please report any link which fails.