Vaccination with the quadrivalent human papillomavirus (HPV) vaccine targeting girls aged 12-13 years started in Australia in 2007, with catch-up vaccination of 14-26 year olds carried out to 2009. The authors were interested in the programme’s impact on HPV prevalence among women aged 18-35 in 2015. For 2015, the Vaccination Register-confirmed 3-dose HPV coverage was 53.3% (65.0% of 18-24 year olds and 40.3% of 25-35 year olds). The prevalence of vaccine HPV types significantly decreased from 22.7% (2005-2007) to 7.3% (2010-2012) and then to 1.5% (2015) among women aged 18-24 years, and from 11.8% (2005-2007) to 1.1% (2015) among women aged 25-35 years. Therefore the prevalence of vaccine-targeted HPV types has continued to decline among young women, with a substantial fall also occurring in women aged 25-35 years, despite their lower coverage.
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